Rosmarinic Acid Benefits

January 20, 2022

1 Antioxidant effect
Rosmarinic acid has a strong scavenging activity of free radicals in the body and an antioxidant effect. The mechanism of action is: rosmarinic acid competes with unsaturated fatty acids to combine with lipid peroxy groups to terminate the chain reaction of lipid peroxidation and reduce the rate of lipid peroxidation.
2 Antidepressant effects
Rosmarinic acid proliferates and produces an antidepressant-like effect, at least in part, by hippocampal neonatal cells.
3 The antibacterial effect of rosmarinic acid
(1) Inhibition of bacteria: Rosmarinic acid has a significant inhibitory effect on Bacillus subtilis, Luccinococcus and Escherichia coli.
(2) Inhibitory fungi: the inhibitory activity of rosmarinic acid on mycelial growth and spore germination of different phytopathogenic fungi.
(3) Inhibition of mold: Rosmarinic acid extracted from plants has an inhibitory effect on Phytophthora and its mold spores that cause soil-borne diseases, effectively reducing the germination of zoospores.
4 Anti-Inflammatory effects of rosmarinic acid
(1) Anti-nephritis effect: Rosmarinic acid can inhibit the proliferation of mesangial cells and glomerular expansion.
(2) Anti-hepatitis effect: Rosmarinic acid can alleviate lipopolysaccharide (LPS)-induced liver injury and significantly inhibit the increase of plasma transaminase levels, which proves that the liver protective effect of rosmarinic acid is through the removal or reduction of superoxide. or oxidized nitrite rather than by inhibiting TNF-α.
(3) Anti-pneumonic effect: Rosmarinic acid inhibits diesel exhaust particulate-induced neutrophil retention and lung injury characterized by interstitial edema.
(4) Anti-arthritis effect: Rosmarinic acid can inhibit collagen-induced arthritis and significantly reduce the number of arthritis and affected joints.
(5) Anti-periodontitis effect: Rosmarinic acid can inhibit the formation of bacterial plaque, thereby preventing chronic gingivitis.
(6) Anti-dermatitis effect: Rosmarinic acid has a relieving effect on atopic dermatitis, also known as atopic eczema or atopic eczema.
5 Antiviral effects of rosmarinic acid
(1) Anti-herpes virus: rosmarinic acid shows special activity on type I and type II herpes simplex virus, and is an effective ingredient for controlling herpes disease. , but also rapidly combined with the viral coat protein, thereby inactivating the virus.
(2) Anti-HIV: Rosmarinic acid can inhibit the activity of HIV-1 (human immunodeficiency virus 1) integrase.
(3) Anti-encephalitis virus: Rosmarinic acid can reduce the mortality rate of mice with Japanese encephalitis virus, significantly reduce the viral load, and make the virus difficult to spread.
6 Anti-Cancer and anti-tumor effects of rosmarinic acid: Rosmarinic acid inhibits the expression of CCL11 and CCR3 by inhibiting the activity of β-kinase and the activation of nuclear factor kappa B-related genes to achieve the purpose of anti-tumor.
7 Anti-allergic effect of rosmarinic acid: Rosmarinic acid can inhibit allergic inflammation induced by microallergens.
8 Antioxidative effect of rosmarinic acid: Rosmarinic acid has good free radical scavenging and antioxidant effects.
9 Antithrombotic and antiplatelet aggregation effects of rosmarinic acid: Rosmarinic acid can inhibit the formation of malondialdehyde in human platelets in vitro, and its IC50 value is 3.37nmol/L, indicating that rosmarinic acid has antiplatelet aggregation activity.
10 Antidepressant Effects of Rosmarinic Acid
11 Anti-radiation and anti-ultraviolet effect of rosmarinic acid: Rosmarinic acid can be used as a photoprotectant to play the role of anti-radiation and anti-ultraviolet
12 Other effects of rosmarinic acid
(1) Stabilizing effect on color
(2) Inhibitory effect on hyaluronidase
(3) Inhibitory effect on xanthine oxidase
(4) Liver protection
(5) Inhibition of angiogenesis
(6) Prevent arteriosclerosis
(7) Prevent memory damage
(8) Used as cosmetics

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