Pharmacological effects of Rhodiola rosea extract

Salidroside is a compound extracted from the dried roots and rhizomes or dried whole herbs of Rhodiola rosea, which has the functions of preventing tumors, enhancing immune function, delaying aging, anti-fatigue, anti-hypoxia, and Anti-Inflammatory properties. Radiation, two-way regulation of the central nervous system, repair and protection of the body and other functions. Often used as a treatment for chronically ill and frail susceptible patients. Clinically used for the treatment of neurasthenia and neurosis, to improve attention, memory, high altitude polycythemia, hypertension; as a neurostimulant, to improve intelligence, improve autonomic-vascular dystonia, muscle weakness, etc.; For diseases with increased free radicals, such as tumors, radiation damage, emphysema, senile cataract, etc.; also as a tonic agent for impotence, etc.; salidroside preparations are also used in sports medicine and aerospace medicine, used in various Health protection of workers under special environmental conditions.

1. Anti-fatigue effect: Oral administration of Rhodiola rhodiola can prolong the pole climbing time, swimming time and load swimming time of mice. It can shorten the time required for recovery after fatigue, improve enzyme, RNA and protein levels, so that muscles can recover as soon as possible after fatigue.
2. Effects on the central nervous system: Rhodiola can normalize the content of serotonin in mice under swimming conditions, that is, the content of the central nervous system from the normal dune is corrected or reaches the normal level. Mice injected with salidroside (30-300mg/kg) can reduce the level of serotonin.
3. Anti-hypoxia effect: Oral administration of the extracts of Rhodiola rosea, Rhodiola serrata, and Rhodiola crimsonum can make the experimental animals show obvious antagonism to various hypoxia modes, and its effect is stronger than that of ginseng and Acanthopanax senticosus .
4. Anti-aging effect: The alcohol extract of Rhodiola rosea can improve the activity of red blood cells and liver SOD in rats, and has a tendency to increase the activity of myocardial SOD. Red wild flax flies drinking Rhodiola rosea extract can significantly prolong their lifespan, and the lifespan extension rate is better than that of ginseng. Rhodiola can promote the proliferation of 2BS cells and reduce the death rate, can inhibit the lipid peroxidation of rat cells and enhance the activity of serum superoxide dismutase.
5. Anti-tumor: Rhodiola has a certain inhibitory effect on S180 cells. Within the range of non-toxic and side effects, this effect increases with the increase of concentration. Continuous oral administration of Rhodiola rosea extract can reduce the carcinogenic damage of erythromycin to the small intestine wall of mice, and improve the body's Anti-Cancer ability.
6. Detoxification effect: salidroside has the effect of antagonizing strychnine poisoning, and can improve the survival rate of mice after strychnine poisoning by 50%; it also has the effect of antagonizing coryneform toxin, and can fight against tetanus and other various Bacterial toxins increase the survival time or survival rate of mice taking potent poisons, sodium cyanide, and sodium nitrite.