Aloe Vera Extract Powder Aloe Emodin

What is aloe-emodin?
Aloe-emodin, melting point 223-224°, easy to sublimate. It is soluble in acetaldehyde, benzene, hot ethanol, dilute ammonia, sodium carbonate, and sodium hydroxide aqueous solution. Easily soluble in hot ethanol. It is yellow in ether and benzene, and crimson in ammonia and sulfuric acid.

Benefits of Aloe-Emodin:
Description of anti-tumor activity
In recent years, domestic and foreign scholars have been interested in the anti-tumor effect of aloe-emodin. The main anti-tumor activity is concentrated on neuroectodermal tumors, liver cancer, lung squamous cell carcinoma, skin Merkel cell carcinoma, gastric cancer, leukemia, and other tumors. The Anti-Cancer range is wide. Aloe-emodin has an inhibitory effect on P388 leukemia cells and prolongs the survival period. One of its mechanisms of action is to inhibit the biosynthesis of DNA, RNA, and protein in cancer cells.
Antibacterial activity
At a concentration of 1.5-25mg/ml, aloe-emodin has inhibitory effects on Staphylococcus, Streptococcus, Diphtheria, Bacillus subtilis, Anthrax, Bacillus paratyphi, Shigella, etc. Among them, it is the most sensitive to Staphylococcus and Streptococcus, and it is antibacterial. The effective concentration is 15-25ug/ml. The in vitro inhibitory concentrations of Staphylococcus aureus 209P, Escherichia coli, and Shigella flexneri were 7.5 mg/L and 600 mg/L, respectively, and their antibacterial effects were bacteriostatic rather than bactericidal. One of its mechanisms of action is to inhibit electron transport in the mitochondrial respiratory chain.
Aloe-emodin has a strong inhibitory effect on the nucleic acid and protein synthesis of Staphylococcus aureus. Aloe-emodin has a strong inhibitory effect on common clinical anaerobic bacteria. Among them, it can inhibit the growth of common fragile strains by 90% to 100%, and its MIC is slightly higher than metronidazole. At a concentration of 8μg/ml, 76%～91% of anaerobic bacteria can be inhibited.
Immunosuppressive effect
Aloe-emodin can inhibit the production of biological antibodies, inhibit the ability of carbon particle clearance, reduce the weight of immune organs, reduce the number of white blood cells, and reduce the function of peritoneal macrophages. In vitro, the concentration of 100μg/ml has a significant inhibitory effect on [3H]-TDR and [3H]Urd incorporation into lymphocytes.
Diarrhea
Aloe-emodin has a strong laxative activity. Intestinal bacteria metabolize aloe-emodin, rhein, rhein anthrone, the latter has a strong laxative effect. Clinically used as a laxative, it has the effect of increasing appetite and laxative effects on the large intestine. According to foreign medical reports, aloin is hydrolyzed into aloe-emodin under the action of parasitic bacteria in the human body. This aloe-emodin stimulates the peristalsis of the intestinal wall. At the same time, due to the change of osmotic pressure, it is beneficial to the elimination of waste from the intestinal tract, thereby achieving irritation. Laxative, this stimulating and purging effect has a special effect on constipation and hemorrhoids. Especially for middle-aged and elderly constipation, the treatment effect is more obvious.
Other effects
It has the effect of making hair soft and shiny, relaxing and refreshing, and removing dandruff.
In the mutagenicity test of hamster fibroblasts, this product has a genotoxic effect.
It can protect the teak from termites.

Company Information

Xi'an Natural-Field Bio-technique Co., Ltd is a technology-driven enterprise, who dedicates to the research, production and selling of Plant Extract, Animal Feed ingredients，cosmetic ingredients and Health Care Ingredients，etc. Over the years, our company positions at producing high quality, fine technique, cutting-edge products, adheres to the concepts of asset-light, high technology and team work principle, with scientific management methods and strict products standards, making great progress in the health-care field.