Antibacterial activity of Ginkgo biloba extract

Numerous studies have shown that Ginkgo biloba extract has antibacterial effects on various plant pathogenic fungi (such as Xanthomonas oryzae persimmon, rice blast, pear rust, corn anthracnose, citrus scab, citrus penicillium, etc.) The size of the effect is different due to the different extraction methods of the antibacterial active ingredients of Ginkgo biloba and is related to the concentration of the antibacterial active ingredients in the extract of Ginkgo biloba. Lin Qinghong conducted an indoor antibacterial experiment in the preliminary research on the indoor antibacterial and insecticidal effects of Ginkgo exodia Phytophthora spp., Chinese cabbage anthracnose pathogen, Capsicum wilt pathogen, Capsicum anthracnose pathogen, Sclerotium aubergine, Blackspot pathogen of cabbage), equipped with a certain gradient concentration of Ginkgo biloba exodia culture medium, which can inhibit the bacteria of Ginkgo exodia extract The effect is studied. The results showed that Ginkgo biloba extract has an antibacterial effect on 8 main pathogens, and the antibacterial effect of the original solution and the Ginkgo biloba explants extract at a concentration of 5 times dilution is 100% (the growth rate of 8 pathogens is 0), the control group The germs grow normally. At the same time, the antibacterial effect of 8 kinds of pathogens on the medium diluted with 10 times the concentration of ginkgo extract reached 45% to 84%. Among them, the antibacterial effect of Strelitzia anthracnose was the best, reaching 84%. The antibacterial effect of anthracnose is the weakest, at 45%.

2.2　The antibacterial effect of Ginkgo biloba extract on common pathogenic bacteria in animals
effect
At present, most of the research on the antibacterial effect of Ginkgo biloba extract has focused on its antibacterial effect on common pathogenic bacteria in animals. Bacteriostasis of bacteria such as Pasteurella multocida. Various studies have shown that GBE has a good antibacterial effect on common animal pathogenic bacteria, and the antibacterial effect of Ginkgo biloba extract is currently the most studied. The antibacterial effect of GBE on Escherichia coli is better than that of gentamicin, enrofloxacin, sulfadiazine, and tylosin, but not as good as streptomycin and kanamycin; GBE's antibacterial effect on Pasteurella multocida The effect is better than ciprofloxacin, gentamicin, sulfadiazine, tylosin, but not as good as streptomycin and kanamycin; GBE has a better antibacterial effect on Staphylococcus aureus than kanamycin, but Less than streptomycin, ciprofloxacin, gentamicin, enrofloxacin, sulfadiazine, tylosin. Staphylococcus aureus is highly sensitive to GBE, and Pasteurella multocida and E. coli are moderately sensitive to GBE.
2.3 　 In vitro antibacterial effect of Ginkgo biloba extract on Porphyromonas gingivalis
The study of the in vitro antibacterial effect of Ginkgo biloba extract on Porphyromonas gingivalis can provide a pharmacological basis for the study of new pure Chinese medicines for the treatment of periodontal pain. There are relatively few studies on the antibacterial effect of spores, which provides a good prospect for the future development and application of Ginkgo biloba extract. Studies have shown that the same concentration of Ginkgo biloba extract has a greater antibacterial effect on Porphyromonas gingivalis than Escherichia coli and Staphylococcus aureus. The antibacterial effect of spore bacteria has greater practicability.